Oprah May Rock on Over to a New Guest Role

First Jennifer Aniston, now Oprah Winfrey?On the heels of Aniston landing a 30 Rock guest gig, Winfrey is in final talks to appear on the show — and would appear in the second episode, says E! Online.If Winfrey inks the deal, she would likely be playing herself, primarily in scenes with Fey. She also might find herself caught in a feud between Tracy Jordan and Jenna. Fey has long been hoping to collaborate with the mega-mogul. In March, she told the New York Post she was pining for QT with Winfrey. "I want Oprah to play my best friend," Fey said. "I want to spend time with Oprah, and I don't know what I need to do to make that happen." — Anna DimondRelated:• Jennifer Aniston's 30 Rockin' Role? Liz Lemon's Stalker• Scoop! Jennifer Aniston Is Ready to 30 Rock

TV GuideNews Sept. 4, 2008 at 1:03 a.m. PT