Sherlock Holmes and Dr. Watson (Arthur Wontner, Ian Hunter) help a young lady whose father is missing, and they discover that his disappearance may be tied to a giant pearl she received from a mysterious stranger. Isla Bevan, Miles Malleson. Directed by Graham Cutts and Rowland V. Lee. Also known as "The Sign of the Four" and "The Sign of the Four: Sherlock Holmes' Greatest Case."