1 of 16 Dimitrios Kambouris/WireImage.com
Everyone remembers brothers Ben and Casey Affleck side by side in Good Will Hunting.
2 of 16 Steve Granitz/WireImage.com
Beyonce and Solange Knowles show nothing but sisterly love.
3 of 16 Kevin Mazur/WireImage.com
Britney and Jamie Lynn Spears have shared plenty of time in the spotlight.
4 of 16 Gary Gershoff/WireImage.com
Both David and Patricia Arquette have found success on the big and small screen.
5 of 16 John Sciulli/WireImage.com
Hilary and Haylie Duff tie music and acting together.
6 of 16 Jeff Vespa/WireImage.com
Jack and Kelly Osbourne have certainly made an impression on the American entertainment industry.
7 of 16 Kevin Mazur/WireImage.com
Jake and Maggie Gyllenhaal are both well-known for their film work.
8 of 16 Michael Caulfield/WireImage.com
Jessica and Ashlee Simpson have conquered everything from singing to acting to fashion.
9 of 16 Lester Cohen/WireImage.com
Kate and Oliver Hudson brighten up the red carpet with their unforgettable smiles.
10 of 16 Denise Truscello/WireImage.com
The Kardashian sisters have allowed fans to see their world through their reality show.
11 of 16 Jamie McCarthy/WireImage.com
Ali and Lindsay Lohan share some gorgeous features, but will they both end up in rehab
12 of 16 Dimitrios Kambouris/WireImage.com
Luke and Owen Wilson know how to make audiences laugh with their big-screen ventures.
13 of 16 Kevin Mazur/WireImage.com
Mary-Kate and Ashley Olsen have been in the spotlight since Full House. Talk about a full bank account!
14 of 16 John Sciulli/WireImage.com
Nick and Aaron Carter both have a love for music, but can Aaron step out from Nick's shadow
15 of 16 Lester Cohen/WireImage.com
Nick and Drew Lachey take Hollywood by storm with their good looks and brotherly love.
16 of 16 Chris Weeks/WireImage.com
Paris and Nicky Hilton have always supported each other through the good, the bad and the ugly. That's hot!