Based on the Pokémon franchise created by Satoshi Tajiri, the film revolves around Tim Goodman, a 21-year-old insurance adjuster. He gave up his dream of being a Pokémon trainer after the death of his mother and his estrangement from his father Harry, a police detective. Tim is told by Harry's friend, Detective Hideo Yoshida, that Harry was killed in a car accident. Tim goes to his father's apartment in Ryme City, a place where humans and Pokémon live together in harmony. There he meets Harry's police partner, an amnesiac talking Pikachu. The two see they are uniquely equipped to communicate with one another and join forces on a thrilling mission - find out what has really happened to Harry.