17 Episodes 2007 - 2008
In the fourth season of ABC's popular medical drama, Meredith (Ellen Pompeo), Cristina (Sandra Oh), Alex (Justin Chambers) and Izzie (Katherine Heigl) graduate to resident status, while George (T.R. Knight) must repeat his intern year after failing his exam. That's not George's only problem: He must also deal with the fallout of betraying his marriage vows to Callie (Sara Ramirez) as he and Izzie try to figure out if they truly are more than friends. Callie lets the stress of her marriage get to her, and it affects her ability to perform as chief resident, a position that Bailey (Chandra Wilson) coveted. Bailey's own marital woes come to a head when her little boy is hurt in an accident at home, while the Chief (James Pickens Jr.) makes strides in repairing his marriage after his ill niece returns to the hospital. Cristina deals with the pain of her failed wedding to Burke by throwing herself into her other love, cardiothoracic surgery. But much to her dismay, Erica Hahn (Brooke Smith) is the new head of this department, and Cristina and Erica clash. Also new on staff is Lexie Grey (Chyler Leigh), George's fellow intern and Meredith's half sister, whom Meredith does her best to avoid. Meredith is on the outs with Derek (Patrick Dempsey), which leaves him free to pursue a nurse named Rose (Lauren Stamile). Meanwhile, a group of nurses whom Mark (Eric Dane) has dated band together to try and stop his promiscuous ways. This prompts Mark to want to change, but he's not the only one looking for self-improvement---Meredith begins therapy with Dr. Wyatt (Amy Madigan). She then reconnects with Derek on a professional level as they work on clinical trials on patients with brain tumors. Alex also reconnects with someone as former patient and love interest Rebecca (Elizabeth Reaser) reenters his life. However, things with her eventually turn complicated, for reasons he doesn't see at first.
A Change Is Gonna Come
Thu, Sep 27, 2007 62 mins
Cristina returns from her "honeymoon" (with Meredith) and begins looking for Burke. At the hospital, new chief resident Callie welcomes a new batch of interns---including George, who is repeating his intern year, and Meredith's half sister Lexie (Chyler Leigh). Meanwhile, Richard resumes his post as chief of surgery, while Bailey tries to acclimate herself to her new duties at the hospital; Derek, at an impasse with Meredith, looks to fellow doctors for friendship.
Thu, Oct 4, 2007 62 mins
The residents and interns treat the victims of an apartment-building explosion, while Alex investigates its cause; Mama Burke (Diahann Carroll) returns to collect her son's things while Cristina gets rid of her wedding presents; Lexie Grey (Chyler Leigh) tries to have a heart-to-heart with an unwilling Meredith; Callie is overwhelmed with her duties as chief resident while Bailey searches for an outlet for her pent-up leadership skills. Archie: Ben Vereen.
Let the Truth Sting
Thu, Oct 11, 2007 62 mins
George's skill level at the hospital impresses the new interns, who don't know his "repeater" status. But life isn't as simple at home, where George feels he must tell Callie about his indiscretion with Izzie. Meanwhile, Meredith halfheartedly helps Lexie with her first emergency patient; and Mark and Richard attempt a radical new surgery to save a woman's ability to speak. Dr. Norman Shales: Edward Herrmann.
The Heart of the Matter
Thu, Oct 18, 2007 62 mins
Adele Webber (Loretta Devine) rushes the niece who had her prom at Seattle Grace back to the hospital for treatment; Izzie reveals her feelings for George to a mutual friend, and the reaction is not what she expects; Derek shows Cristina how to be a better teaching resident; and Norman (Edward Herrmann), an intern who's considerably older than his colleagues, misdiagnoses one of Meredith's patients.
Haunt You Every Day
Thu, Oct 25, 2007 60 mins
Halloween is a day of surprises (both good and bad) for the doctors of Seattle Grace: Alex receives an unexpected visit from Ava/Rebecca (Elizabeth Reaser); Meredith is convinced that her mother's ashes are haunting her; Cristina is snubbed by a surgeon she admires; and Callie announces George and Izzie's affair to their fellow doctors. Dr. Norman Shales: Edward Herrmann. Jack: David Clennon. James: Rocky Carroll. Olivia: Sarah Utterback.
Kung Fu Fighting
Thu, Nov 1, 2007 60 mins
With his wife filing for divorce, the Chief decides he needs to spend a "gentlemen's evening" with his fellow male surgeons; Cristina and Izzie heatedly compete for the same surgeries (and the favor of new cardiothoracic chief Erica Hahn); Meredith treats the survivor of a skydiving accident; the doctors treat two injured finalists in a bridal-gown promotional competition.
Physical Attraction...Chemical Reaction
Thu, Nov 8, 2007 67 mins
George and Izzie's romantic chemistry is put to the test; Derek asks for more than just sex from Meredith; Mark develops an unexpected crush on a fellow surgeon; and Callie's job as chief resident is jeopardized after she delegates many of her duties to Bailey.
Thu, Nov 15, 2007 62 mins
The ER is filled with teenagers after a school-bus crash; Bailey treats a patient who was her high-school crush; Derek dates a fellow doctor; and Thatcher (Jeff Perry) sees Meredith for the first time since his second wife Susan's death.
Crash Into Me
Thu, Nov 22, 2007 60 mins
Part 1 of 2. Meredith and the Chief struggle to save paramedics injured in an ambulance crash; Bailey treats a patient who refuses her help; Ava (Elizabeth Reaser) returns to see Alex---and meets his new girlfriend. Nick: Seth Green.
Crash Into Me
Thu, Dec 6, 2007 62 mins
Conclusion. Meredith works furiously to save a paramedic trapped in an ambulance; Lexie literally holds the life of a patient (Seth Green) in her hands; Derek must rely on nurse Rose (Lauren Stamile) to save a patient when an OR computer breaks down; and Bailey keeps Tucker (Cress Williams) waiting while she operates on a white supremacist . Ava: Elizabeth Reaser.
Lay Your Hands on Me
Thu, Jan 10, 2008 62 mins
While Bailey's family faces a medical trauma, the doc faces a marital one. Meanwhile, a surprise visit from George's mother (Debra Monk) comes as a shock to both Izzie and Callie; a faith healer challenges Erica and Alex's beliefs in Western medicine; and Derek must deal with the aftermath of his kiss with Rose (Lauren Stamile). Elizabeth: Glenne Headly.
Where the Wild Things Are
Thu, Apr 24, 2008 62 mins
Meredith, Alex, Izzie and Cristina compete in a surgical contest, with Bailey judging; George and his new roommate, Lexie, adjust to their squalid apartment; and Callie finds a friend in Erica Hahn. The episode takes place six weeks after Derek and Meredith ended their relationship and Derek began dating Rose (Lauren Stamile). Dr. Wyatt: Amy Madigan. Otis: Cheech Marin.
Piece of My Heart
Thu, May 1, 2008 62 mins
Addison (Kate Walsh) returns to Seattle Grace to perform a surgery and is surprised at the changes in her former coworkers' lives; Meredith and Derek's clinical trial has its first patient; Ava/Rebecca (Elizabeth Reaser) returns with news for Alex. Dr. Wyatt: Amy Madigan.
Thu, May 8, 2008 62 mins
A "date-and-tell" policy is instituted at Seattle Grace after nurses complain about Mark's trysts, but Callie turns to him in a time of need. Meanwhile, Preston Burke's latest career accomplishments force Cristina to confront her feelings about him; and Derek and Meredith admit a military man into their clinical trial. Kevin: John M. Jackson. Adele: Loretta Devine. Dr. Wyatt: Amy Madigan. Rose: Lauren Stamile.
Losing My Mind
Thu, May 15, 2008 62 mins
Dr. Wyatt won't let Meredith give up on therapy; the Chief is adamant about Erica performing a risky surgery on his mentor; Alex learns the truth about Rebecca's condition. Meanwhile, Cristina continues to act contrary to her nature, even cleaning her apartment, after receiving news of Burke.
Thu, May 22, 2008 60 mins
In Part 1 of the two-part fourth-season finale, the surgeons work as a team to free a young man from a block of quick-drying cement. Meanwhile, Meredith and Derek get an ultimatum concerning their clinical trial; Izzie and Alex spar over his care for a depressed Rebecca; Lexie finds out crucial info about George's status at Seattle Grace; and Cristina gets her mojo back after Meredith gives her the sparkle pager. Beth: Jurnee Smollett.
Thu, May 22, 2008 60 mins
In the conclusion of the fourth-season finale, Derek and Meredith operate on Beth (Jurnee Smollett) without the chief's approval; Alex rushes Rebecca to the hospital after she cuts herself, and clashes with Izzie over her care; Mark forces Callie to face her feelings about Erica; and Lexie forces George to face his surgical future. Meanwhile, the case of the young man in concrete gives Cristina a chance to display her newly regained mojo. Adele: Loretta Devine.