Join or Sign In
Sign in to customize your TV listings
By joining TV Guide, you agree to our Terms of Use and acknowledge the data practices in our Privacy Policy.
Grey's Anatomy Season 1 Episodes
Season 1 Episode Guide
9 Episodes 2005 - 2005
In the first season of this medical drama, a group of surgical interns, including Meredith Grey (Ellen Pompeo), Cristina Yang (Sandra Oh), Izzie Stevens (Katherine Heigl), George O'Malley (T. R. Knight) and Alex Karev (Justin Chambers), begin working at Seattle Grace Hospital. On the night prior to her first day, Meredith goes to a local bar and sleeps with a man she never expects to see again. The man turns out to be neurosurgeon Derek Shepherd (Patrick Dempsey), one of her new bosses. Izzie accuses Meredith of sleeping with her boss to get ahead, and as the season progresses, a complicated romance develops between Meredith and Derek.
Episode 1
A Hard Day's Night (Pilot)
Sun, Mar 27, 2005 60 mins
The first 48-hour shift for the surgical residents is chronicled in the series pilot, in which Meredith meets surgeon Derek Shepherd before she discovers he's her boss. She also has trouble with her first case, a teenage girl who's having seizures. And George tries his hand at an appendectomy.
Episode 2
The First Cut Is the Deepest
Sun, Apr 3, 2005 60 mins
While Meredith decides who gets to move into her house, she must also deal with the grisly souvenir of a patient's brutal rape. And her visit to the nursery leads to a conflict with a pediatric intern. Meanwhile, Cristina and Alex develop their bedside manners, in a manner of speaking; George has a depressing day overseeing codes; Izzie runs into a language barrier with one of her patients; and Burke finds out why Webber hired Derek.
Episode 3
Winning a Battle, Losing the War
Sun, Apr 10, 2005 60 mins
A daredevil bicycle-messenger race leaves in its wake (and in the ER) an array of patients, including a banged-up cyclist who hits on Meredith and a brain-dead hit-and-run victim. The tragedy this man represents gets to Izzie. But who'll get his liver? One possibility is an older gay cancer patient (Keith David), who likes to flirt with George, who doesn't know how to handle it. Meanwhile, the cyclist isn't the only guy hitting on Meredith: Derek just won't let up. Viper: Callum Blue.
Episode 4
No Man's Land
Sun, Apr 17, 2005 60 mins
While Izzie deals with the fallout from a racy magazine spread, Cristina pushes for aggressive treatment for a cancer patient (Anna Maria Horsford) who happens to be Meredith's mother's long-time scrub nurse, and Meredith and Shepherd treat a man who accidentally shot nails into his head.
Episode 5
Shake Your Groove Thing
Sun, Apr 24, 2005 60 mins
While Izzie's planning a party (and treating a patient with an obstructed bowel), Meredith assists in a heart operation---and does something she shouldn't. George's patient is an ex-smoker (Kathryn Joosten) with emphysema and Alex's is a young man (Brent Sexton) who says he has back pain. He's addicted to painkillers and Alex doesn't like that one bit. Hank: Jonathan Scarfe. Mr. Patterson: Barry Shabaka Henley.
Episode 6
If Tomorrow Never Comes
Sun, May 1, 2005 60 mins
The doctors treat a woman (Alex S. Alexander) with a 65-pound tumor and a man (Bruce Weitz) with Parkinson's disease. Also, Meredith's relationship (if that's what it is) with Shepherd gets her in trouble with Bailey, while George ponders asking Meredith for a date, and Izzie has her own affair of the heart. Annie's Mom: Jane Galloway Heitz. Mr. Levangie's Daughter: Lara Phillips.
Episode 7
The Self-Destruct Button
Sun, May 8, 2005 60 mins
Someone's been sleeping in Meredith's bed again, and when roomies Izzie and George find out who it is, they're not at all happy. But George is assuaged when Shepherd picks him to assist in a tricky and unusual brain operation on a 2-year-old girl. Meanwhile, Izzie must perform a bronchoscopy on a guy who swallowed his girlfriend's car keys. On purpose. And Alex, a former college wrestler, meets another ex-grappler in the clinic. The guy had asked a friend to shoot him because "I like the scars."
Episode 8
Save Me
Sun, May 15, 2005 60 mins
Shepherd's tight-lipped about himself to Meredith, which adds to the tension between them when they disagree about a mountain climber with an unexplained paralysis. Meanwhile, a psychiatric patient with seemingly psychic powers psychs out Izzie; a pregnant woman with breast cancer befuddles Cristina; George meets his match when he has to intubate a patient; and Burke tells an Orthodox Jewish teenager with a heart defect that only a pig valve can save her.
Episode 9
Who's Zoomin' Who?
Sun, May 22, 2005 60 mins
Webber has eyesight problems, George gets a girlfriend (and a rash) and Meredith gets a surprise. Meanwhile, Burke's best friend (Wayne Wilderson) is a patient at Seattle Grace. And Izzie and Cristina must perform an unpleasant procedure they've never done before on an alcoholic. Addison: Kate Walsh.
