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48 Episodes 2008 - 2009
Episode 1
A documentary crew captures more action than they bargained for when a teenager sets a terrifying chain of events in motion. Adam risks everything to play the hero, but is it enough for Jessica?
Episode 2
55 mins
The situation on the estate escalates and, after spotting Tess on some video footage, Charlie goes to look for her. Adam wants Jessica's decision.
Episode 3
Abs is quick to take the blame when Stacey is accused of injuring a young girl. In the midst of chaos, a familiar face arrives.
Episode 4
Adam's suspicions about Nick Jordan grow, Charlie tries to persuade Abs to reconsider his decision and Zoe is left reeling by her test results.
Episode 5
It's Dixie's first day back and she tries to act normally. But the facade begins to crack as she starts taking dangerous risks in the ambulance.
Episode 6
Abs is still struggling to come to terms with Stacey's death and takes out his frustration at work.
Episode 7
Abs wakes up in a police cell - battered and bruised. In contrast, Adam finds himself in the company of a young woman.
Episode 8
Tess is forced to have faith in Charlie when a new nurse is appointed.
Episode 9
Dixie treats an overdose, and a dying father has a chance to make peace with his son - but he also has a score to settle.
Episode 10
A road accident gives Ruth and Toby the chance to prove themselves to Jordan. Dixie discovers Jeff has split up with his wife.

Episode 11
In an episode omitted from the U&Drama rerun, November 2025, we see Dr Nick Jordan undergoing a strange procedure which presumably has something to do with his as yet undisclosed medical condition; a man with Tourette's antagonises the folk in the flat below with his faulty plumbing; paramedic Zana moans about having to attend chavs; Jessica & Zoe have buried their differences and are now friends; there is disruption in the department due to building work; cheeky chappie new boy Jay gets a telling off from future partner Ruth. Casualty Car Crash 225 occurs when a car swerves to avoid a young girl doped up on crystal meth. Paramedic Curtis breaks into the house of an acquaintance who's dealing the drugs. Under lock down conditions, Dr Nick successfully carries out an operation on the Tourette's man. Curtis takes on/off girlfriend Alice to see his brother's grave. Beautiful but beastly admin babe Marilyn Fox makes her final appearance. Ruth and Nick snog.
Episode 12
Jordan is feeling rueful after his night of passion with Ruth. Dixie worries about what the impending TV documentary will reveal.
Episode 13
A terrible accident forces Adam to confront his past. Meanwhile tensions simmer between Ruth and Jordan.
Episode 14
When Jessica collapses at work, she admits to Tess she is pregnant. Ruth is worried Toby isn't coping after his night with Ben.
Episode 15
Sean tells the entire department that Jessica is pregnant.
Episode 16
Toby discovers that rumours about him and Ben have reached epidemic proportions. Jessica and Sean continue to lock horns over their move, with damaging consequences.
Episode 17
60 mins
Adam learns some shocking news and takes steps to find out the truth. Adam gets shocking news, and carefree Zoe is brought down to earth. Meanwhile, Ruth contemplates the realities of Christmas alone.
Episode 18
Toby tries to make amends by withdrawing the allegation against Ben but is later left trapped and alone in a perilous situation. Jessica is relieved when Sean appears to forgive her over her affair with Adam.
Episode 19
Memories of past misdemeanours flood back as Toby fights for his life in the river. A train crash brings chaos to the staff at Holby, while Ruth questions her abilities.
Episode 20
Zoe ignores Sharice's pleas with devastating consequences. Alex clashes with Adam after getting cold feet over his impending operation.
Episode 21
Jordan makes a confession to Alex, Jessica receives alarming news and Zoe deals with the fallout from Abby and Finn's deaths.

Episode 22
When a stabbing victim is brought into A&E, it seems that Curtis knows the culprit. But his refusal to talk to the police threatens to wreck his relationship with Alice. Zoe struggles to connect with Sharice following Abby's death.
Episode 23
Jordan faces a dilemma when Adam's brother, Alex, is rushed in following an overdose. Jordan is faced with a difficult decision. Curtis struggles to reveal his feelings.
Episode 24
Devastated by Alex's death, Adam sets out to prove a defiant Jordan's culpability.
Episode 25
Tess and Jordan realise Adam isn't coping well when he brings Alex's ashes into the office, and Curtis' plans for a romantic Valentine's day with Alice are thwarted by an unwelcome face.
Episode 26
Alice tells Tess that she and Curtis are no longer an item and Big Mac foils a robbery attempt.
Episode 27
Jordan tries to cover his condition. An apparent cash windfall leads Kelsey to triumphantly hand in her notice.
Episode 28
Kelsey tries to make amends with her colleagues. Meanwhile, Adam's skills are put to the test by an unstable addict's efforts to procure methadone.
Episode 29
Jessica receives news about her children, and Ruth realises she's become too preoccupied with work. Alice decides to fight for her man.
Episode 30
Big Mac reflects on events leading up to his arrest, and makes a decision.
Episode 31
It's Kelsey's last shift and the gang has organised a surprise party for her. Zana makes an important decision.
Episode 32
Self-medication isn't helping Jordan's worsening condition, Adam deals with a challenging patient and Tess's suspicions are aroused.
Episode 33
Jordan is diagnosed and throws himself into work. Zoe tries to balance work and motherhood.
Episode 34
Jordan plans to sacrifice Adam, Zoe makes a hard decision, and Jessica goes into labour.
Episode 35
Adam's resignation sparks a shocking reaction, and Jessica gets an unwelcome visitor.
Episode 36
Jordan's secret is revealed, and Jessica has a shocking revelation about baby Harry.
Episode 37
Alice's kindness to a patient puts her life in danger and Jeff tries to build bridges with his wife. Jordan and Adam begin their new regime.
Episode 38
Alice's life hangs in the balance, and Curtis is determined that someone will pay. But how far will he go to get revenge.
Episode 39
There's friction between Jordan and Zoe, but as they get closer, what will the evening bring? Alice has a shock on her return.
Episode 40
Jeff is forced to confront the end of his marriage. Meanwhile, Polly is thrown in at the deep end.
Episode 41
Ruth goes out of her way to impress her potential new boss. Meanwhile, Jordan gathers the courage to reveal his secret to Zoe.
Episode 42
Jeff decides to fight for his kids. Jay teaches Ruth how to connect. Alice's wedding plans spiral out of her control.
Episode 43
Jordan's illness gets the better of him. Meanwhile, Sean forces Jessica to make a difficult choice.
Episode 44
Ruth's web of lies begins to unravel. Jordan gets a nasty shock.
Episode 45
Jordan is left reeling after some life-changing news, and faces a difficult decision. Zoe, meanwhile, makes a serious mistake, Jessica returns from Saudi and Curtis chooses his best man.
Episode 46
After learning the truth about Jordan's suspension, Adam's professional conscience is piqued. Curtis's preparations for his stag night are interrupted when he learns that Tony has been released from prison.
Episode 47
Curtis and Alice's wedding day is thrown into turmoil when he finds Tony has been murdered. Curtis flees the scene, with Alice agreeing to become his fellow fugitive. A familiar face endangers Jessica and Adam's relationship.
Episode 48
Alice's wedding day falls apart as she sticks by Curtis in his hour of need. Meanwhile, Jordan discreetly makes his exit.