The series is based on the 2018 novel of the same name by Chris Bohjalian. American flight attendant Cassie Bowden is a reckless alcoholic who drinks during flights and spends her time off hooking up with strangers, including her passengers. Her anchorage is her best friend Annie, a lawyer. It all starts when Cassie wakes up in her hotel room in Bangkok, with a hungover from the last night and with a dead body of a man who was on her last flight lying next to her. She has no idea what has happened and is unable to piece the night together, so she begins to wonder if she could be the killer. Too scared she does not call the police, cleans up the crime scene as much as she can and joins the other airline crew traveling to the airport.
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