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24 Episodes 1967 - 1968
Episode 1
Sat, Sep 16, 196752 mins
With the client only asking for Intertect's best man, Lew assigns Mannix to the case despite Mannix constantly breaking the rules. Mannix is dismayed to learn that it is a pure systems case, that of a missing person. The case gets more complex as he learns the missing person is Angela Dubrio, the daughter of aged semi-retired Palm Springs racketeer Sam Dubrio, the client, and that the case is not just that Angela is missing, but that she has been kidnapped in Sam's wife of twenty-two years and Angela's mother, Louise Dubrio, having received a ransom demand of $500,000. Mannix continues with the case despite kidnappings, by law, needing to be handled by the police, Mannix coming to the realization that Sam, in his position, not able to go to the police. Louise provides further information to Mannix as to why Sam seems so clinical in his approach to Angela's kidnapping, despite he willing to pay the ransom. Regardless, Mannix knows that the kidnappers have set up the ransom drop so that the contact person cannot be followed. But Mannix plans to use that ransom drop as a means indeed to lead him to the kidnappers. He will discover that not all that appears on the surface is reality with regard to the kidnapping.

Episode 2
Sat, Sep 23, 196752 mins
A potential candidate for governor, a successful businessman employs Intertect to probe his background. His rationale: he wants to see if the detective agency can turn up any dirt that could be used by political opponents. If Intertect can't find any, he reasons his political opponents wouldn't be able to do so, either. Mannix follows his own leads while his Intertect colleagues probe the obvious. As Mannix's investigation progresses, people he has interviewed turn up dead. Mannix may be the next person on the hit list.

Episode 3
Sat, Sep 30, 196752 mins
He asked for specifically, Mannix is about to decline the offer to work on a divorce case, that is until he learns the client is Gloria Farnsworth née Newman, his serious girlfriend until she married wealthy Victor Farnsworth three years ago. In inferring she wants to resume a relationship with Mannix after all is said and done, Gloria wants a quiet but in her words "dirty" divorce in her directive to Mannix being to dig up any dirt on her soon to be former husband, she suspecting there having been marital infidelity on his part. Shortly after starting work on the case, Mannix discovers that in the process he has been set up to take a fall in being implicated in a murder, the police indeed naming him publicly as the only suspect and thus is a wanted man. On the run with Lew's help, Mannix necessarily changes his focus to finding out who the real murderer is i.e. who set him up and why, the most obvious candidate being Gloria herself.
Episode 4
Sat, Oct 7, 196752 mins
A group of businessmen approach Intertect. They say they want to approach a former colleague and offer him $1 million for a new formula. Mannix is suspicious the clients aren't telling the truth. He befriends the daughter of the man the businessmen want to approach and she falls for him. Mannix keeps digging and discovers the clients are really Nazi hunters. Or are they really Nazis? Mannix must find the answer and save the life of the daughter.
Episode 5
Sat, Oct 14, 196752 mins
A little girl wishes to "rent a detective" to prove that her father, who is on Death Row, is innocent. Mannix takes the case, working on his own time, and will have to do without Intertect's help. Mannix romances the mistress of a reclusive rich man at whose estate the murder took place. The detective must cope with a web of deceit to find out what really happened.

Episode 6
Sat, Oct 21, 196752 mins
A model spots a Latin man she met on a vacation but he flees. She hires a former boyfriend, Joe Mannix, to track down the man. But the case quickly becomes more complicated. In Mannix discovering the man's true nature, the lives of both Mannix and his client are now endangered.
Episode 7
Sat, Oct 28, 196752 mins
Mannix is hired by an old friend to find his college-age daughter, who is living in a commune. Mannix soon discovers the commune has secrets that can be deadly to discover. One college basketball player has already died. And why is a hoodlum so interested in what transpires at the commune?

Episode 8
Sat, Nov 4, 196752 mins
A 26-year-old woman, worth $10 million, hires Intertect to do a background check on her boyfriend. It turns out the woman has spent 10 years in a mental hospital and seems on the verge of cracking up. Mannix suspects something more sinister. The woman is surrounded by shady characters. The detective concludes one of them seeks to drive her back to the mental hospital.

Episode 9
Sat, Nov 18, 196752 mins
Mannix, on the mend after a gunshot wound has one foot in a cast, is given a routine assignment by Intertect boss Lew Wickersham: get the signature of a man named Amos Silo on a legal document. The detective takes a bus to a small town but finds a chilly reception whenever he inquires about the man or his ranch. The town is hiding something. As Mannix digs deeper, he discovers dead cattle are part of the mystery. The question is whether he'll survive to find out the rest.
Episode 10
Sat, Nov 25, 196752 mins
Mannix is working on a child custody case that should be routine. It isn't. It begins with Mannix barely saving the life of the boy who is the subject of the custody fight. As Mannix's investigation continues, it becomes clear the boy's father is the target of killers, including one attempt by using explosives. Yet, the father isn't rich. Mannix must figure out the motive before the boy and father are harmed.

Episode 11
Sat, Dec 2, 196752 mins
A burglar steals notebooks from a psychiatrist but double crosses an accomplice and takes the notebooks for himself. One of the patients hires Mannix and Intertect after being blackmailed. Mannix's client is a movie studio art director who has a secret in his past. The trail turns deadly.

Episode 12
Sat, Dec 9, 196752 mins
A crusading newspaper editor is preparing an explosive expose of a state legislator. But a man who supposedly had the documentation has fled just as the story went to press. The editor hires Intertect, which sends Mannix to work on the case. Mannix and Intertect boss Wickersham come to doubt whether the legislator is corrupt. But somebody is responsible for a trail of bodies and Mannix is determined to find out who.
Episode 13
Sat, Dec 16, 196752 mins
With only two of his colleagues, Captain of Detectives Tom Randolph and Lieutenant Barry Frohm with Central Division, in the know about what he is doing but neither agreeing with the move, Police Inspector Frank Kyler secretly hires Mannix under cloak and dagger to deal with an internal police matter. What Mannix knows from the news is that a man named Myles Stroud was murdered in a drive by shooting, but what the media did and does not know is that Stroud was an undercover police officer. In that undercover operation, he struck up a romantic relationship with a woman named Mavis Miller, who has since jumped bail. Stroud was working on a tip that an unknown number of cops were on the take, Miller handling the payoffs for the police. With Stroud and Miller now known to the crooked cops, Miller is as good as dead wherever she is in she not able to run forever. With Kyler having evidence that she is holed up in a rooming house a few hundred miles away, the location only known by Kyler, Mannix is tasked with finding her and bringing her back to provide testimony on the crooked cops. One other person external to the police that is interested is bail bondsman Monty Kelbo in he having lost his $10,000 unless Mavis is found. Mannix discovers in finding an uncooperative Mavis that the hole within the police department is probably bigger than Kyler suspects in people in wait wanting to kill Mannix and Mavis. Mannix is thus tasked with trying to discover who the holes in the police department are in addition to getting Mavis back safely.
Episode 14
Sat, Dec 30, 196752 mins
Mannix infiltrates an alcohol-rehabilitation center in Mexico. His client is a young woman who fears her father is being swindled. Intertect has devised a cover identity so that Mannix poses as an alcoholic who has been committed there by an Intertect operative posing as his wife. Mannix discovers a confidence man is also posing as a patient. In the middle of the case, another patient turns up dead and Mannix finds out there have been several unsolved murders nearby. If Mannix isn't careful, he could be the next victim.
Episode 15
Sat, Jan 6, 196852 mins
Vain, arrogant, fading movie star Anne Marion calls a press conference to announce plans for an autobiography. Then, a bomb goes off. The actress hires Intertect and, after a look at available operatives, decides Mannix is her man. The assumption was the bomb was a publicity stunt. Mannix visits one of Anne's ex-husbands, who performs special effects work. The bomb was supposed to be a dud. Mannix is convinced that someone wants to do the actress harm. She has three suspicious ex-husbands, one of whom is an arrogant hothead, the other who employs shady and violent bodyguards. Mannix decides to make himself a target by having Anne's college-age daughter take the diary of the actress and letting the ex-husbands know it. Is one of them the potential killer? Or is it somebody else?

Episode 16
Sat, Jan 13, 196852 mins
Three people are brutally murdered. The evidence points to David Tate. When a potential client approaches Intertect about trying to prove Tate innocent, Mannix agrees to take the case. The private detective finds himself caught in between the police and whoever is framing Tate.
Episode 17
Sat, Jan 20, 196852 mins
An Intertect security chief apparently has been killed while driving. At almost the same time, an explosion at an Intertect client has killed a technician and destroyed a new laser device. Mannix suddenly is thrust into the case while Intertect chief Wickersham begins acting erratically, the side effect of medication for an infection. Mannix concludes that the Intertect security man may have sold out, along with somebody at the client. Mannix later finds that the Intertect security man is still alive. Mannix, though, isn't having an easy time. The Intertect chief's behavior turns worse and he gets into a brutal fight with Mannix. Afterward, an injured Mannix confronts a woman who was having an affair with the Intertect security man. She drugs him and Mannix is on the verge of falling into unconsciousness as someone is coming to the woman's apartment.

Episode 18
Sat, Jan 27, 196852 mins
A doctor for Intertect arrives and treats Mannix's injuries. The physician also informs Mannix that Lew Wickersham has been taking steroids prescribed to treat an infection. That's why Wickersham's behavior has been erratic. Mannix and Wickersham separately probe the conspiracy that has left three people dead. If they aren't careful, the death toll will rise again.

Episode 19
Sat, Feb 3, 196852 mins
Mannix quits Intertect after Wickersham agrees to accept a case from suspected gang boss Aram Karmalis. Striking out on his own, Mannix agrees to help a young woman. But it turns out that Mannix is now working a different angle of the same case.
Episode 20
Sat, Feb 10, 196852 mins
Down on his luck Bernie Farmer is married to Rose whose brother is a mobster. As the criminal is about to be paroled, Bernie decides to open a box his brother-in-law had entrusted to him, but he finds the box empty. Mannix and Intertect boss Lew Wickersham, against their better judgment, agree to help Bernie find what was in the box. Mannix sets himself up as a target on the pretense that he has the box and its contents. The detective will endure multiple assaults from the mobster's cohorts as he tries to solve the case.
Episode 21
Sat, Feb 17, 196852 mins
Mannix is hired to investigate a supposed miracle that has occurred on land owned by a mobster. When a man turns up dead and the mobster's thugs beat on Mannix, the miracle's legitimacy seems highly doubtful. But the motives for faking the miracle are murky, at best. The mobster doesn't stand to gain financially. But Mannix is determined to find the truth.
Episode 22
Sat, Mar 2, 196852 mins
A man named Spinelli shows up severely injured at a hospital emergency room, asking for Mannix. The detective arrives. He's never seen Spinelli before in his life. From this odd beginning, Mannix will be beaten, suspended by Intertect and shot at with a spear gun as he tries to solve a mystery extending back more than 20 years.
Episode 23
Sat, Mar 9, 196852 mins
A mystery writer finds a suicide note in his home -- supposedly written by himself. The author specializes in stories that are based on actual cases and he's working on a new novel taken from an unsolved murder. Mannix tries to protect the author, but the writer insists on trying to work on the case. This complicates things greatly for Mannix. In addition, Mannix must deal with a collection of shady characters as he tries to find the would-be killer.
Episode 24
Sat, Mar 16, 196852 mins
Wealthy art collector Calvin Norris, while visiting an artist friend, sees a woman modeling for a sculptor in the studio across the alley. Norris is shocked. The woman looks exactly like the subject of a Renoir painting he owns. He tries to get to the woman but she is gone before he can get to the sculptor's studio. Norris hires Mannix and Intertect to track the woman down. Norris is more interested in her than the possibility his painting is a forgery. Mannix, relying more on legwork than Intertect's computers, finds the woman, who, it turns out is really an artist and only models occasionally. It also turns out that Lang, the sculptor, is prone to violence. Mannix is convinced Linda is in danger and he's determined to crack the conspiracy.