Stuck in a small Appalachian town, a young woman's only escape from the daily grind is playing advanced video games. She is such a good player that a company sends her a new video game system to test...but it has a surprise in store. It unlocks all of her dreams of finding a purpose, romance, and glamour in what seems like a game...but it also puts her and her family in real danger.
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Tokiko Mima, nicknamed "Key," is a 17-year-old girl living in the Japanese countryside who, despite her human-like appearance, is a robot. When Key's grandfather Dr. Murao Mima passes away, he leaves her a dying message, telling her that she can become a real girl if she is able to make thirty thousand friends. Thus, Key moves from the quiet Mamio Valley to the busy streets of Tokyo, where she soon runs into her childhood friend Sakura Kuriyagawa.
Gi Seo is a renowned doctor at the top of his profession, but he's racked with guilt because he wasn't able to save his girlfriend, Ji Min, who was HIV-positive. He escapes to work on a small island and fulfill Ji Min's dying wish: to find a little girl named Bom who she accidentally infected with HIV while she was a medical intern. Bom lives on the island with her single mom Young Shin and grandfather, who has dementia.
Hotshot plastic surgeons Dr. Sean McNamara and Dr. Christian Troy experience full-blown midlife crises as they confront career, family and romance problems.
Doomsday follows the daily lives of the residents of a millennial cult and explores the gray area where youthful idealism evolves into deadly extremism.