"All of Us" is inspired by the domestic adventures of entertainment superstars Will Smith and Jada Pinkett-Smith and reflects a new generation's enlightened attitude toward the extended-family dynamic with humor, sensitivity, and heart. Robert James is an entertainment reporter for a local Los Angeles television station whose best friend is also his publicist, the thrice-divorced Dirk. Robert is handsome, smart, and a thoroughly modern man in his thinking, as he should be, considering his romantic and parental entanglements. On the verge of finalizing his divorce from the self-absorbed Neesee, the mother of their endearing five-year-old son Bobby, Jr., he is madly in love with Tia, a funny, clever kindergarten teacher. This humorous and heartwarming comedy is a fresh, timely look at many young parents' new, compassionate attitude toward how divorced parents raise their children together.
Mona and Dee Dee are half-sisters with the same father who didn't really know each other when they were little and are complete opposites, but as adults they live in the same apartment building and at least try to bond.
Mother and daughter Nikki and Kim Parker both attend Santa Monica College. Nikki dropped out of school when she got pregnant with Kim, but now, as Kim prepares to head to college, Nikki decides that it's her turn to finish getting her education.
Retired Navy commander Jim Kennedy is divorced and has a teenage son. He takes over the famous cruise ship, where he and his crew tackle various scenarios with different passengers every week.
Young acting pastor David Randolph (David Ramsey) is designated to Compton, California's African American Church of Life. Initially, the majority of the church's members balk at the young pastor's new position and resent him for replacing their former pastor. With help from the church's secretary, Vera Hudson (Rose Jackson Moye), Randolph attempts to reunite the church and help his congregation.
To take his mind off his divorce, antimatter physicist Gus Lloyd started programming an action video game where he was the hero, his ex-wife Lauren Ashborne was the sidekick, and they would fight Sebastian Jackal, a Satanic figure who wanted to destroy the world with an army of thugs, based on the people who made Gus' life a living hell. The antimatter experiments Gus and his friend Peter Rucker were running went haywire, reading the game's villain file and sending them into the real world to act out their programming. Gus, Lauren, and Peter are then forced to play the game for real.