This mini-series follows the story of Covert One agent Rachel Russell who is double-crossed in Berlin while investigating the outbreak of a virus. After killing the two dirty agents, she escapes but needs to find someone trustworthy that she can hand over the vials to. At the same time, Lt. Colonel Jonathan Smith, a biochemistry expert, and his fiancée Sophie Amsden, get drawn into the dark underworld of bio-terrorism and seditious plots when an extremely aggressive variant of the Ebola virus is unleashed on the American public. Jon has to return to the US to try to research a cure in a race against time to save the population.