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20 Episodes 2019 -
Season 5 of the drama series opens with the aftermath of the car accident that almost killed Manning (Torrey DeVitto) and Halstead (Nick Gehlfuss). Meanwhile, Rhodes (Colin Donnell) suspects Bekker (Norma Kuhling) of killing his father, Maggie (Marlyne Barrett) struggles to accept her cancer diagnosis, Charles (Oliver Platt) gives up on his honeymoon to treat a patient, and Choi (Brian Tee) and April (YaYa DaCosta) have a pregnancy scare. As the season progresses, the team of doctors has to deal with several challenges: performing surgery in the dark when the power goes out, training new residents, and treating the effects of a flesh-eating bacteria in a cross-over episode with "Chicago Fire" and "Chicago P.D."
Episode 1
Wed, Sep 25, 2019 45 mins
In the Season 5 premiere, Will and Natalie face the aftermath of a horrific car incident and are left to battle for their lives. An investigation is launched following the suspicious death of the elder Cornelius Rhodes, Dr. Rhodes' father. Maggie receives life-changing news. Dr. Charles cuts his honeymoon short to tend to a young patient he suspects might have schizophrenia.
Episode 2
Wed, Oct 2, 2019 60 mins
Dr. Choi and Dr. Charles face difficult decisions as a dying man tries to preserve his future life with a controversial scientific method. Dr. Marcel and April clash over how to handle a mysterious patient and Will questions Natalie's capabilities. Sharon assigns a nurse to shadow Maggie, much to her dismay.
Episode 3
Wed, Oct 9, 2019 60 mins
A dying man tries to preserve his future life with a controversial scientific method. Dr. Marcel and April clash over how to handle a mysterious patient and Will questions Natalie's capabilities. Sharon assigns a nurse to shadow Maggie, much to her dismay.
Episode 4
Wed, Oct 16, 2019 60 mins
Part 2 of a three-show crossover event: An entire apartment complex is forced into quarantine when cases of the deadly virus turns into an epidemic. P.D. chases a lead that could point to a case of bioterrorism and Will gets dangerously close to the suspect.
Episode 5
Wed, Oct 23, 2019 60 mins
Dr. Choi and Dr. Marcel don't see eye-to-eye over the treatment of a patient's chronic pain and rumors start to circulate about Maggie. Dr. Manning works to help a young boy, but her treatment suggestions are challenged by the parents who believe in only using holistic remedies.
Episode 6
Wed, Oct 30, 2019 60 mins
Dr. Manning's actions with a recent patient lead to serious repercussions. April and Noah disagree over a patient who is injured after a beating. Dr. Charles is visited by a childhood friend with a surprising revelation.
Episode 7
Wed, Nov 6, 2019 60 mins
Dr. Charles and Dr. Halstead sink their teeth into a bloodthirsty case; Dr. Marcel and Maggie throw a traditional crawfish boil for the staff and a new relationship blossoms.
Episode 8
Wed, Nov 13, 2019 60 mins
Maggie gets unsettling news about a new friend and breaks protocol to support him. One of the doctors from the Med family is rushed into emergency surgery after a violent assault. A social media influencer lets his users vote on medical advice, forcing Dr. Charles to make a decision.
Episode 9
Wed, Nov 20, 2019 60 mins
April receives unfortunate news that makes her question her future with Ethan. Dr. Charles and Maggie see tough times on the horizon. Natalie's memory from the accident starts to return.
Episode 10
Wed, Jan 8, 2020 60 mins
Dr. Halstead's world is thrown into turmoil when a former patient resurfaces. April has a secret she considers confessing to Ethan. Dr. Charles tries to maintain his focus during a difficult time.
Episode 11
Wed, Jan 15, 2020 60 mins
After a major accident at O'Hare, the E.D. is concerned one of their own is in mortal danger. Will's proposal for a safe injection site goes to the board for consideration. Natalie and Goodwin become concerned for Gwen.
Episode 12
Wed, Jan 22, 2020 60 mins
The team deals with the aftermath of a school bus crash. Dr. Charles worries Dr. Halstead is putting his medical license in jeopardy. Maggie helps a friend in need.
Episode 13
Wed, Feb 5, 2020 60 mins
Two brothers in critical condition are rushed into the hospital by their parents. Dr. Choi, April and Dr. Charles are left to tend to their care and to piece together what actually transpired. Dr. Manning becomes suspicious of a new mother entering the E.D. Dr. Halstead’s tireless activities at the safe injection site start to take a toll on his work.
Episode 14
Wed, Feb 12, 2020 60 mins
Dr. Manning and Dr. Marcel disagree over an abusive husband. Dr. Halstead struggles with ethics and his decision to work at the safe injection site. Dr. Charles and Elsa reveal a misdiagnosis that may change a family's life.
Episode 15
Wed, Feb 26, 2020 60 mins
Dr. Charles and Dr. Manning treat a patient who is fully invested in pretending to be someone other than himself. Noah begins to doubt his abilities as a doctor. Dr. Marcel and Dr. Choi are faced with a tough ethical decision. Dr. Halstead puts his faith in an addict.
Episode 16
Wed, Mar 4, 2020 60 mins
A convicted murderer's escape hits close to home when several members of the team find themselves in danger. Dr. Charles and Dr. Halstead continue to clash over patient treatment plans. Dr. Choi and April discover the truth about a patient's scam. Maggie finally receives some good news.
Episode 17
Wed, Mar 18, 2020 60 mins
Marking the series milestone 100th episode, Dr. Manning and Dr. Charles assist in a complicated case helping a 4-year old who they quickly learn is no stranger to the ED. Dr. Marcel and Dr. Choi tend to a police officer with a mysterious gunshot wound to the abdomen. Relationships are put to the test as secrets are revealed.
Episode 18
Wed, Mar 25, 2020 60 mins
Dr. Charles and Goodwin fear Dr. Halstead is repeating his past mistakes when a patient with early-onset Alzheimer's is brought into the E.D. Maggie and Ben become concerned when one of Ben's students is admitted. Dr. Manning and Dr. Marcel treat a terminally ill patient and disagree over the best course of action.
Episode 19
Wed, Apr 8, 2020 60 mins
Dr. Charles evaluates a 15 year old who is brought into the E.D. after an apparent fall off an overpass. Will sides with Dr. Asher on a risky treatment plan. Tensions run high between Dr. Choi and Dr. Marcel.
Episode 20
Wed, Apr 15, 2020 60 mins
Dr. Crockett is visited by two New Orleans detectives who have questions about his past. Dr. Choi puts his life in danger to save a child. Dr. Charles gives fatherly advice to his young daughter.