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Special Agent Will Trent of the Georgia Bureau of Investigations (GBI) is determined to use his unique point of view to make sure no one is abandoned like he was.

Six months into his career as a cop, John Nolan will be put to the test as he looks to figure out what kind of cop he ultimately wants to be.

Fresh out of medical school, John "J.D." Dorian, Christopher Turk and Elliot Reid join the staff of Sacred Heart Hospital, only to realize how much they still have to learn.

The tradition of passion, intrigue and adventure takes place in the fictional town of Port Charles, in upstate New York.

A young surgeon with autism and savant syndrome uses his extraordinary gifts to save lives and challenge skepticism.

Each week, viewers saw the gritty reality of life in a New York City Police unit, as the officers go about their work with a grim determination, and a willingness to break the same laws that they're supposed to be enforcing. Two partners, Detectives Andy Sipowicz (Dennis Franz) and John Kelly (David Caruso) (later replaced by Bobby Simone (Jimmy Smits)), were the central characters in this weekly Police drama, and personified very different approaches to their difficult job. Sipowicz's brash gruffness (covering an emotional vulnerability) was tempered by the precise and controlled demeanor of the two partners with whom he has worked.