Paramedics Steve and Dennis' duties are more or less the same every night: they tend to people who are victims of violence, have overdosed, or are hungover. One day, however, things change as people dying from perplexing circumstances begin to emerge. Soon, the common thread among the cases is discovered: a new recreational drug called Synchronic. The two friends find themselves in the middle of the mystery when Dennis' oldest daughter, Brianna, disappears after taking the drug.