Joelle and Camille decide to go on a rampage, picking up and seducing numerous men and then doing things like destroying their cars. Eventually, they set their sights on a "higher" goal and decide to do in an entire town. Meanwhile, it becomes evident that a sinister medical researcher, Dr. Worms, has infected promiscuous Joelle with a sexually transmitted disease he invented for the sole purpose of becoming the man who finds its cure, which he hopes will make him beloved, famous and rich.