A Copenhagen family man becomes increasingly erratic while taking part in an experimental drug test to treat depression in this intense psychological drama. Mikael (Ulrich Thomsen) is a loving husband and father who just can't relax. Unable to sleep, Mikael agrees to take part in a drug test for a new antidepressant. At first the drug seems to work wonders, though before long Mikael is isolating himself from family and friends, and a disturbing new personality begins to emerge.