Born William, and known as Bill in his youth, but began going by Willem in high school
Left college to join Milwaukee-based Theatre X, which was one of the longest-running experimental theater groups in the country when it disbanded in 2004
In the late 1970s, joined the Wooster Group, an experimental theater group in New York City; its founding members included Spalding Gray and Elizabeth LeCompte, with whom Dafoe had a 27-year relationship (and one son)
Was briefly considered for the role of the Joker in Tim Burton's 1989 Batman film
Provided the voice for James Bond's nemesis Nikolai Diavolo in the video game James Bond 007: Everything or Nothing