First acting role came in a grade-school production of Johnny Appleseed
Went on to study theater in college
Member of Steppenwolf Theatre Company in Chicago, IL, since 1979; debuted in the 1980 play Bonjour, La Bonjour
Honored with her first Jeff Award, given for outstanding accomplishments in Chicago theater, in 1982
In 1986, made directorial stage debut in the two-play series Lydie Breeze
Made Broadway debut in the 1990 stage version of The Grapes of Wrath
First TV role was on the ABC comedy Roseanne in a 1992 episode called "Therapy
" Made cinematic debut in the 1992 comedy Mo' Money
Rejected role of Mattie Fae in the problematic comedy August: Osage County four times before she agreed to do it; her portrayal earned her a Tony Award
Landed the role of Peggy in the 2010 CBS comedy Mike & Molly