As a teenager, took singing and dancing lessons at New York's Professional Children's School, and worked as a cabaret singer for a time after dropping out of college
Starred in the 1990 film Cry-Baby as Pepper Walker, a character written specifically for her by writer-director John Waters
Appeared in both the 1988 and 2007 versions of the movie Hairspray
In the first she played the leading role of Tracy Turnblad, and in the latter made a cameo as a William Morris talent agent
Produced the 2007 documentary The Business of Being Born, which explores childbirth in the modern world
The film includes footage of her home birthing her second son, Owen
Competed in the 13th season of ABC's Dancing with the Stars with partner Derek Hough