- As a youngster, she sang solos in the Beulah Baptist Church Choir in southwest Philadelphia.
- Her music groups have included the Ordettes (1960), the Blue Belles (1961-65), Patti LaBelle & the Bluebelles (1965-70) and LaBelle (1970-77).
- Her fellow singers in the Blue Belles and Patti LaBelle & the Bluebelles were Nona Hendryx, Sarah Dash and Cindy Birdsong, though Birdsong left in 1967 to join The Supremes.
- Appeared in Broadway's Your Arm's Too Short to Box With God alongside Al Green in 1982.
- Made her film debut in 1984's A Soldier's Story.
- Received a star on the Hollywood Walk of Fame in 1993.
- Won a Soul Train Lifetime Achievement Award in 1997.
- Received the Songwriters Hall of Fame Lifetime Achievement Award in 2003.
- Has authored Don't Block the Blessings: Lessons of a Lifetime, Patti's Pearls: Lessons on Living Genuinely, Joyfully, Generously and numerous cookbooks.
- Has been a spokesperson for the American Diabetes Association, the National Minority AIDS Council and the National Cancer Institute.
- Started selling her own line of sauces, marinades and spices in 2007.
- 1986, Emmy — Outstanding Individual Performance in a Variety or Music Program: Nominee
- 1985, Emmy — Outstanding Individual Performance in a Variety or Music Program: Nominee
- 1991, Grammy — Best Female R&B Vocal Performance: Winner
- 1998, Grammy — Best Traditional R&B Vocal Performance: Winner
- Armstead Edwards — Ex-husband
- Bertha Holte — Mother
- Henry Holte — Father
- Stanley — Son
- Barbara — Sister
- Dodd — Son
- Jackie — Sister
- Zuri — Son
- Vivian — Sister
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