- Made his Broadway debut as a replacement performer in Elia Kazan's play Crime in 1927, where he met his wife, Peggy Lloyd.
- Was part of the Mercury Theatre acting troupe.
- Played Cinna in Orson Welles' staging of Julius Caesar at the Mercury Theatre in 1937.
- His first TV appearance was in Alfred Hitchcock's Saboteur in 1942.
- Suffered as a result of the blacklist, and his career didn't recover until Hitchcock hired him as a director for Alfred Hitchcock Presents.
- His character on St. Elsewhere, Dr. Daniel Auschlander, was originally only supposed to appear in 4 episodes; Lloyd became a series regular and stayed with the show for the entire run.
- 1970, Emmy — Outstanding Dramatic Series: Nominee
- 1974, Emmy — Outstanding Special - Comedy or Drama: Nominee
- Josie Lloyd — Daughter
- Peggy Lloyd — Wife (deceased)
- Attended New York University, New York, New York, United States
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