- Began acting at age 8, appearing in commercials and print ads
- Has said that he loved Salisbury steak until he had to eat it, sometimes cold, through 50 takes of a scene for acclaimed 2003 drama 21 Grams.
- He and his younger brother, Marc, played Robert Duvall and Michael Caine's nephews in the family drama Secondhand Lions (2003).
- Landed his first series-regular role in 2006, playing Oliver Oken on Hannah Montana.
- Released his self-titled debut album in June 2009.
- Cowrote and performed the theme song for his Disney Channel series PrankStars.
- Writes music with his older brother, Mason, who sings for the techno-pop band Metro Station.
- Marc Musso — Brother
- Sam Musso — Father
- Mason Musso — Brother
- Kathy Musso — Mother
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