- Is fluent in French and Mandarin Chinese; spent eight months during college living in Beijing.
- At Harvard in 1985, was one of the founding members of a coed a cappella group called the Harvard-Radcliffe Veritones.
- Made her acting debut on a 1990 episode of Law & Order, which starred her father, Paul Sorvino. Despite having her scenes cut, she was still able to secure her Screen Actors Guild card.
- Turned down a three-year contract in 1993 to star in the daytime soap Guiding Light.
- Her portrayal of an entomologist in the 1997 film Mimic led to her name being used for a chemical defense of the sunburst diving beetle: Mirasorvone.
- Her charitable efforts include work on the behalf of AIDS research, UNICEF and a coalition to abolish human trafficking.
- 1996, Emmy — Outstanding Lead Actress for a Miniseries or a Special: Nominee
- 1996, Golden Globe — Best Performance by an Actress in a Supporting Role in a Motion Picture: Winner
- 2006, Golden Globe — Best Performance by an Actress in a Miniseries or Motion Picture Made for Television: Nominee
- 1997, Golden Globe — Best Performance by an Actress in a Miniseries or Motion Picture Made for Television: Nominee
- 1995, Oscar — Best Performance by an Actress in a Supporting Role: Winner
- 1995, Screen Actors Guild Awards — Outstanding Performance by a Female Actor in a Supporting Role: Nominee
- 1996, BAFTA Film Awards — Best Actress in a Supporting Role: Nominee
- 1996, Critics' Choice Awards — Best Supporting Actress: Winner
- Holden Paul Terry Backus — Son
- Lucia Backus — Daughter
- Christopher Backus — Husband
- Quentin Tarantino — Ex-significant Other
- Amanda Sorvino — Sister
- Mattea Angel Backus — Daughter
- Olivier Martinez — Ex-significant Other
- Lorraine Davis — Mother
- Paul Sorvino — Father
- Johnny Backus — Son
- Michael Sorvino — Brother
- Harvard University, Cambridge, Massachusetts, United States (BA in East Asian Studies, 1989)
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