- Initially trained to become a ballerina, but switched to acting at 15 years old.
- Got her first break in 2004, appearing in the Australian drama All Saints.
- Received a Best Young Actor nomination from the Australian Film Institute for her role in the 2006 film Suburban Mayhem.
- Director Tim Burton said he cast her as the title role in Alice in Wonderland because she has "an old-soul quality" to her.
- Loves photography.
- 2006, Australian Film Institute Awards — Young Actor Award: Nominee
- 2015, Canadian Screen Awards — Performance by an Actress in a Supporting Role: Nominee
- 2009, Australian Film Institute Awards — International Award for Best Actress: Nominee
- 2010, Australian Film Institute Awards — International Award for Best Actress: Winner
- 2010, Independent Spirit Awards — Best Supporting Female: Nominee
- 2014, AACTA Awards — Best Lead Actress: Nominee
- 2010, Screen Actors Guild Awards — Outstanding Performance by a Cast in a Motion Picture: Nominee
- Marzena Wasikowska — Mother
- Kai — Brother
- John Reid — Father
- Jess — Sister
- Jesse Eisenberg — Ex-significant Other