- Worked as a part-time art critic and attended medical school before moving into filmmaking.
- Studied at legendary Italian director Luchino Visconti's Experimental Film Studios.
- Made his directorial debut in 1959 with the Italian-language comedy The Thieves.
- Rose to international prominence in 1979 with Zombi 2 (AKA Island of the Living Dead), billed by producers as an unofficial sequel to George Romero's 1978 classic Dawn of the Dead.
- At the time of his death, was set to direct Wax Mask, inspired by the 1953 Vincent Price classic House of Wax.
- Camilla Fulci — Daughter
- Antonella Fulci — Daughter
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