- Was left with partial hearing loss as a child, due to an infection.
- As a bodybuilder, trained with Arnold Schwarzenegger, and starred with him in 1976 documentary Pumping Iron.
- Bodybuilding contest wins include Mr. America, and Mr. Universe, twice.
- Played briefly with the CFL's Toronto Argonauts.
- Took on a comical turn, playing himself, in the acclaimed 2009 comedy film I Love You, Man.
- Worked as a personal trainer for Michael Jackson.
- In 2010, took part in the controversial police work of Sheriff Joe Arpaio, who spearheaded Arizona efforts to combat illegal immigration.
- Owns Ferrigno Fitness, a manufacturer of fitness equipment.
- Brent Ferrigno — Son
- Carla Green — Wife
- Victoria Ferrigno — Mother
- Susan Groff — Ex-wife
- Shanna Ferrigno — Daughter
- Matthew Ferrigno — Father
- Louis Ferrigno Jr. — Son
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