His father was a policeman who was gunned down in a bar while off duty in 1975
Moved to Hollywood after quitting college and worked as a receptionist for a nursing agency before successfully starting up a health-care agency of his own by the age of 22
Acting on the advice of a producer working for singer Prince, began a career as a music-video casting director
With his former partner Billy Hopkins, adopted the baby twins of his jail-bound brother when they were 3 days old
Formed production company Lee Daniels Entertainment in 1984; its first feature effort, Monster's Ball (2001), earned two Academy Award nominations, including a Best Actress win for Halle Berry
In 2004, produced public service announcements encouraging young people of color to vote
Directorial debut came with the crime thriller Shadowboxer (2005), a violent and sexually explicit film about professional assassins who are also lovers
The first African-American to receive a nod from the Director's Guild of America and only the second nominated for an Academy Award in the Best Director category for Precious: Based on the Novel 'Push' by Sapphire (2009)