- Lived in Norway, Nigeria, Cameroon, Zanzibar and France while growing up.
- One of her first roles was as a New Orleans prostitute in Neil Jordan's Interview With the Vampire (1994).
- Founded the production company The Public with Michael Sheen.
- Best-known for playing Cherie Blair in the 2006 drama The Queen and for her award-winning role as Rose Fitzgerald in the British TV series North Square.
- Due to pregnancy, she was unable to take the role of Bellatrix Lestrange in Harry Potter and the Order of the Phoenix (2007) and was replaced by Helena Bonham Carter; she was later cast as Bellatrix's sister Narcissa Malfoy in Harry Potter and the Half-Blood Prince (2009).
- Awarded an OBE (Officer of the Order of the British Empire) in the Queen's New Year Honours List in 2017.
- 2015, Critics' Choice Awards — Best Supporting Actress in a Drama Series: Nominee
- 2013, Olivier Awards — Best Actress in a Supporting Role: Nominee
- Anne McCrory — Mother
- Ian McCrory — Father
- John McCrory — Brother
- Manon Lewis — Daughter
- Catherine — Sister
- Damian Lewis — Husband
- Gulliver Lewis — Son
- University of the Arts, Drama Centre, London, England
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