At the age of 16, won the Junior Mr. Victoria bodybuilding competition.
Landed a role on the long-running Australian soap Neighbours soon after graduating from Geelong College.
Was nominated for Most Promising Actor at the Chicago Film Critics Awards for his American movie debut, the 1997 crime drama L.A. Confidential.
Won Best Actor at the Las Vegas Film Critics Awards and the San Diego Film Critics Awards for the acclaimed 2001 thriller Memento.
Returned to the stage after a seven-year absence as the star of Poor Boy, a 2009 Australian play based on the music of fellow Aussie Tim Finn.
Spoke at the 2011 dedication ceremony for Colin Firth's star on the Hollywood Walk of Fame.
Declined the lead in the 2003 adaptation of Daredevil as he didn't want to play a comic-book superhero, but the role of villainous Aldrich Killian changed his mind and he appeared in Ironman 3 in 2013.
2011, Screen Actors Guild Awards — Outstanding Performance by a Male Actor in a Television Movie or Miniseries: Nominee
1997, Screen Actors Guild Awards — Outstanding Performance by a Cast in a Motion Picture: Nominee
2014, AACTA Awards — Best Lead Actor: Nominee
2011, Emmy — Outstanding Supporting Actor in a Miniseries or a Movie: Winner
2009, Australian Film Institute Awards — International Award for Best Actor: Nominee
2012, AACTA Awards — Best Lead Actor: Nominee
2010, Australian Film Institute Awards — Best Supporting Actor: Nominee
2005, Australian Film Institute Awards — Best Lead Actor: Nominee
2008, Australian Film Institute Awards — Best Lead Actor: Nominee
2010, Screen Actors Guild Awards — Outstanding Performance by a Cast in a Motion Picture: Winner
2012, Golden Globe — Best Performance by an Actor in a Supporting Role in a Series, Miniseries or Motion Picture Made for Television: Nominee