- Joined the Marines after graduating from high school, and served until the end of his enlistment in January 1948.
- After college, moved to New York, where he studied Method acting with Lee Strasberg.
- Made Broadway debut in 1956 at the Longacre Theatre in N. Richard Nash's Girls of Summer.
- Was the original choice to play Blake Carrington in the prime-time TV soap Dynasty (1981-89), but was replaced by John Forsythe during the shooting of the pilot due to creative differences with the producers.
- Best known for playing a wannabe writer opposite Audrey Hepburn's Holly Golightly in Breakfast at Tiffany's (1961), and Col. John "Hannibal" Smith on NBC's The A-Team (1983-87).
- 1961, BAFTA Film Awards — Most Promising Newcomer to Film: Nominee
- Laura Taylor — Wife
- Julie Helen Peppard — Daughter
- Christian Peppard — Son
- Sherry Boucher — Ex-wife
- Bradford Davies Peppard — Son
- Vernelle Rohrer Peppard — Mother
- Elizabeth Ashley — Ex-wife
- George William Peppard Sr. — Father
- Helen Davies — Ex-wife
- Alexis Adams — Ex-wife
- Attended Purdue University, West Lafayette, Indiana, United States; Carnegie Institute of Technology, Pittsburgh, Pennsylvania, United States (1955)