- Spent his early adult life in and out of prison on various drug and robbery convictions; became the welterweight boxing champion of San Quentin.
- Got his start in show business by giving Eric Roberts boxing lessons for the movie Runaway Train (1985).
- Was hired as a consultant on the movie Heat to make sure the bank robbery scenes looked authentic; was later given a role as a member of Robert De Niro's crew.
- Had a cameo in the Jonas Brothers 2008 music video "Burnin' Up.
- Visits high schools and detention centers to speak with at-risk kids and warn them against turning to drug use and crime.
- Has acted in numerous movies for director Robert Rodriguez, who is a distant cousin.
- Gilbert Trejo — Son
- Dan Trejo — Father
- Alice Trejo — Mother
- Debbie Shreve — Ex-wife
- Debbie Trejo — Wife (separated)
- Danny Boy Trejo — Son
- Danielle Trejo — Daughter
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