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Dean gets a mysterious phone call that appears to be from his dad (Jeffrey Dean Morgan), explaining how to get out of the deal, and he decides to follow the advice despite the fact that Sam doesn't believe it was really John on the line.
Sam and Dean investigate zombies in a small Pennsylvania town, where they find a doctor (Billy Drago) with a sinister agenda. Meanwhile, Bobby learns where Bela (Lauren Cohan) is hiding, so Dean confronts her, leaving Sam to deal with the doctor.