- Born to thespian parents.
- Appeared in silent films as a child actor.
- Acted in radio plays at an early age.
- Served as a Marine aerial gunner in World War II.
- Made stage debut in 1946 in the production Heyday.
- Made a riveting appearance as a jealous, obsessive, abusive husband in the 1963 debut of the classic drama series The Fugitive.
- Best known, though, on TV in a very different role, that of a bachelor who raises a nephew and two nieces, in Family Affair, a sitcom that debuted in 1966. He received three Emmy nominations for the role.
- Died of a self-inflicted gunshot wound in 1997.
- Awarded the 2,365th star on the Hollywood Walk of Fame in 2008.
- 1967, Emmy — Outstanding Continued Performance by an Actor in a Leading Role in a Comedy Series: Nominee
- 1969, Emmy — Outstanding Continued Performance by an Actor in a Leading Role in a Comedy Series: Nominee
- 1968, Emmy — Outstanding Continued Performance by an Actor in a Leading Role in a Comedy Series: Nominee
- Robert Keith — Father
- Victoria Young Keith — Wife
- Daisy Keith — Daughter
- Helena Shipman — Mother
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