In 1974, during her first of many summers at the Williamstown Festival, played Nina in The Seagull; 20 years later, appeared as Arkadina in the same play, while Nina was played by daughter Gwyneth Paltrow
Has played Paltrow's mother on screen in the miniseries Cruel Doubt (1992) and the feature film Sylvia (2003)
Played mother to Charlie Sheen and Jon Cryer in the pilot of the sitcom Two and a Half Men; claimed that she didn't have a feel for the role and was replaced by Holland Taylor
Had a recurring role as Will's mother on Will & Grace
Received three Emmy nominations in 2005: Outstanding Guest Actress in a Comedy Series for Will & Grace; Outstanding Lead Actress in a Miniseries or a Movie for Back When We Were Grownups; and Outstanding Supporting Actress in a Drama Series for Huff
She won for Huff
Awards
2006Emmy-Outstanding Guest Actress in a Comedy Series:nominated
2006Emmy-Outstanding Supporting Actress in a Drama Series:winner