- Made her acting debut in the 1985 Italian TV miniseries Dreams and Needs.
- Voted the Most Desirable Actress in Italy in 1996.
- Published her first novel, I Love You Kirk, in 1999.
- Made her feature-film directing debut in 2000 with the drama Scarlet Diva.
- Father Dario Argento directed her in several films, including Trauma (1993) and The Stendhal Syndrome (1996).
- 1997, Nastri d'argento — Best Actress: Nominee
- 1997, David di Donatello Awards — Best Actress: Winner
- 2006, Nastri d'argento — Best Actress: Nominee
- 2015, Taormina Film Fest — Taormina Arte Award: Winner
- 1993, Nastri d'argento — Best Actress: Nominee
- 1995, Nastri d'argento — Best Actress: Nominee
- 2014, Nastri d'argento — Best Script: Nominee
- 1994, Nastri d'argento — Best Supporting Actress: Nominee
- 1994, David di Donatello Awards — Best Actress: Nominee
- Vincent Gallo — Ex-fiancé
- Claudio Argento — Uncle
- Elda Luxardo — Grandmother
- Morgan — Ex-significant Other
- Anna Lou Argento — Daughter
- Dario Argento — Father
- Salvatore Argento — Grandfather
- Anna Ceroli — Half Sister
- Anthony Bourdain — Ex-significant Other
- Michele Civetta — Ex-husband
- Nicola Giovanni — Son
- Michael Pitt — Ex-significant Other
- Daria Nicolodi — Mother
- Fiore Argento — Half Sister
- Rob Cohen — Ex-significant Other
- Fabrizio Corona — Ex-significant Other
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