In 1990, took the lead in an off-Broadway production of Craig Lucas's Prelude to a Kiss, but did not follow the show to Broadway because of film obligations; two years later, reprised the role for the film adaptation, opposite Meg Ryan
Passed on Patriot Games, the sequel to the smash hit The Hunt for Red October, to star in a Broadway revival of A Streetcar Named Desire
Narrated a number of episodes of the popular children's series Thomas the Tank Engine and Friends in the mid-'90s, and appeared as the Conductor in the 2000 feature film Thomas and the Magic Railroad
One of the most popular hosts of Saturday Night Live, clocking enough appearances to warrant his own Best of DVD
An outspoken advocate for a variety of public-policy issues, including the environment and gun control; serves on the board of directors for the Carol M
Baldwin Breast Cancer Research Fund (founded in 1996 after his mother, Carol, successfully battled the disease)
Awards
2018Emmy-Outstanding Supporting Actor in a Comedy Series:nominated
2017Emmy-Outstanding Host for a Reality or Reality-Competition Program:nominated
2017Emmy-Outstanding Supporting Actor in a Comedy Series:winner
2013Screen Actors Guild Awards-Outstanding Performance by an Ensemble in a Comedy Series:nominated
2013Screen Actors Guild Awards-Outstanding Performance by a Male Actor in a Comedy Series:nominated
2013Emmy-Outstanding Comedy Series:nominated
2013Emmy-Outstanding Lead Actor in a Comedy Series:nominated
2013Golden Globe-Best Performance by an Actor in a Television Series - Comedy or Musical:nominated
2012Emmy-Outstanding Lead Actor in a Comedy Series:nominated
2012Screen Actors Guild Awards-Outstanding Performance by an Ensemble in a Comedy Series:nominated
2012Golden Globe-Best Performance by an Actor in a Television Series - Comedy or Musical:nominated
2012Emmy-Outstanding Comedy Series:nominated
2012Screen Actors Guild Awards-Outstanding Performance by a Male Actor in a Comedy Series:winner
2011Emmy-Outstanding Lead Actor in a Comedy Series:nominated
2011Emmy-Outstanding Comedy Series:nominated
2011Screen Actors Guild Awards-Outstanding Performance by an Ensemble in a Comedy Series:nominated
2011Screen Actors Guild Awards-Outstanding Performance by a Male Actor in a Comedy Series:winner
2011Golden Globe-Best Performance by an Actor in a Television Series - Comedy or Musical:nominated
2010Emmy-Outstanding Special Class Program:nominated
2010Emmy-Outstanding Lead Actor in a Comedy Series:nominated
2010Golden Globe-Best Performance by an Actor in a Television Series - Musical or Comedy:winner
2010Screen Actors Guild Awards-Outstanding Performance by a Male Actor in a Comedy Series:winner
2010Screen Actors Guild Awards-Outstanding Performance by an Ensemble in a Comedy Series:nominated
2010BAFTA Film Awards-Best Supporting Actor:nominated
2009Screen Actors Guild Awards-Outstanding Performance by a Male Actor in a Comedy Series:winner
2009Emmy-Outstanding Lead Actor in a Comedy Series:winner
2009Golden Globe-Best Performance by an Actor in a Television Series - Musical or Comedy:winner
2009Screen Actors Guild Awards-Outstanding Performance by an Ensemble in a Comedy Series:nominated
2008Emmy-Outstanding Lead Actor in a Comedy Series:winner
2008Golden Globe-Best Performance by an Actor in a Television Series - Musical or Comedy:nominated
2008Screen Actors Guild Awards-Outstanding Performance by an Ensemble in a Comedy Series:winner
2008Screen Actors Guild Awards-Outstanding Performance by a Male Actor in a Comedy Series:winner
2007Screen Actors Guild Awards-Outstanding Performance by a Male Actor in a Comedy Series:winner