Intermittently suffered from episodes of Bell's palsy, which first appeared when she was 15, then again during her junior year of college
Cofounded a nonprofit theater troupe named Missing Children, for which she penned the play Verbatim; she also acted and served as artistic director
First big-screen role was in director Hal Hartley's 1989 feature debut The Unbelievable Truth, an indie dramedy that became a hit on the festival circuit
Made her feature-film directing debut in 1997 with the black comedy Sudden Manhattan, in which she also starred
Won the U
S
Comedy Arts Festival's Film Showcase Jury Award for Best Director in 2000 for her second feature, the romantic comedy I'll Take You There
Following her death, the Adrienne Shelly Foundation was established to offer scholarships and grants to women studying and working in film