Ellen Pompeo Ellen Pompeo

Ellen Pompeo appeared on Chelsea Lately Wednesday and was about as frank and lively as we've ever seen her.

The Grey's Anatomy actress dishes the dirt about filming sex scenes with Patrick Dempsey, her Boston roots ("Everybody I know has been to prison — including my husband!"), and perhaps most interestingly, the rumors that Katherine Heigl will return to the medical drama.

Check out the clip below.