Susan Tyrell in "Shoot Out" Susan Tyrell in "Shoot Out"

Oscar-nominated Fat City actress Susan Tyrrell has passed away at the age of 67, Austin360 reports.

A friend of the actress tells the site that Tyrrell died on Saturday in her home in Austin, Texas. A cause of death was not immediately available.

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Tyrrell was diagnosed with thrombocythemia, a rare bone marrow disease, in 2000. Though she had both her legs amputated, Tyrrell continued to act, appearing in Masked and Anonymous and Kid Thing.The actress was most famous for her role in John Huston's 1972 boxing drama Fat City, in which she played alcoholic barfly Oma. She earned an Oscar nomination for Best Supporting Actress.

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In addition to her film career, Tyrrell also made appearances on TV shows, including Baretta, Starsky and Hutch and Kojak.