"I can confirm the divorce papers were filed and from Slash's perspective the split is amicable," his rep told the site.
Slash (real name: Saul Hudson) and Ferrar tied the knot in October 2001. They have two children together, 8-year-old London and 4-year-old Cash. He is seeking joint physical and legal custody of both sons.
The former Guns N' Roses member released his first solo album last year and is currently on tour.