Running Wilde Running Wilde

Fox's new romantic comedy Running Wilde is a story of opposites attract.

She's an activist-humanitarian, and he's a buffoonish playboy. After being separated for years, circumstances reunite the childhood sweethearts. Star Keri Russell breaks it down: "He's continued to be rich and act like a teenager, and I've gone on to start all these foundations..."

Co-star Will Arnett says his character's life is, in fact, "meaningless in a lot of ways."

So... why are they attracted to each other? Hint: It's physical!

Will Arnett interviews Will Arnett: "My role model would probably be Kate Moss"

Helping them get together is Steve's nanny Mr. Lunt (Robert Michael Morris), his driver and confidante Migo (Mel Rodriguez), his best frenemy Fa'ad (Peter Serafinowicz) and Emmy's daughter Puddle (Stefania Owen.)

Will Arnett: Running Wilde designed to reveal what a hypocrite Keri Russell is

Check out this exclusive behind-the-scenes clip of the cast talking about the show below:

Check out Will Arnett and Keri Russell at a RUNNING WILDE photoshoot

Go on the set of a photoshoot for Running Wilde starring Will Arnett and Keri Russell.|Running Wilde|Will Arnett|Keri Russell|

Running Wilde premieres on Tuesday, Sept. 21 at 9:30/8:30c on Fox.