Rob Lowe Rob Lowe

Rob Lowe will guest-star in Season 4 of Californication, Showtime announced Monday.

Lowe — best known for his roles on The West Wing and Brothers & Sisters — will play Eddie Nero, a self-obsessed, award-winning movie star who is in contention to play the film version of Hank (David Duchovny). Lowe is slated to appear in one episode, but could possibly recur.

Rob Lowe to exit Brothers & Sisters

Shortly after the announcement that he was leaving Brothers & Sisters, the 46-year-old actor was added to the cast of Parks and Recreation, along with Party Down star Adam Scott.