Robert Wisdom by Paul Schiraldi/HBO Robert Wisdom by Paul Schiraldi/HBO
Prison Break may have killed off half of its cast members last season, but that just means more room for new interesting characters in upcoming episodes. According to Prison Break's star

Wentworth Miller, Another World's Jodi Lyn O'Keefe will join the cast as a mysterious woman named Susan B who interacts with Dominic Purcell's character. "The two of them apparently have a great amount of chemistry on camera," Miller says. Inside the Panama prison where Michael Scofield (Miller) is incarcerated, The Wire's Robert Wisdom will join the cast as Panamanian drug lord Luchero. British import Chris Vance will play an inmate named Whistler, a guy who might have something to do with the conspiracy that got Michael into this mess. And for once Michael will not be the man with the plan. "Michael has always been the smartest guy in the room, but now it's about improvisation and thinking on his feet," Miller says. "It raises the stakes for him and makes for a more intense story." - Reporting by Carita Rizzo