The Firefly actress (deal with it, Homeland fans) will bring to life DC Comics character Dr. Leslie Thompkins, a dedicated doctor and former friend of Bruce Wayne's (David Mazouz) late parents.
Thompkins will be seen putting her medical skills to use at the newly reopened Arkham Asylum's Home for the Criminally Insane when Baccarin's recurring stint begins in early 2015.
What do you think of Baccarin's casting?
Gotham airs Mondays at 8/7c on Fox.
On the set of Gotham: Meet the heroes!