Bruce Boxleitner and Melissa Gilbert Bruce Boxleitner and Melissa Gilbert

Melissa Gilbert and Bruce Boxleitner have separated after 16 years of marriage, her rep tells

"We have loved each other for a very long time and we share four incredible sons together," Gilbert said in a statement. "On behalf of our family we ask to be allowed our privacy during this very difficult time."

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Gilbert, 46, and Boxleitner, 60, married in 1995 and have a 15-year-old son, Michael, who is named after the actress' Little House on the Prairie co-star, Michael Landon.Gilbert also has a 21-year-old son, Dakota, with ex-husband Bo Brinkman, and Boxleitner has two sons, Sam, 30, and Lee, 25, with ex-wife Kathryn Holcomb.

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Gilbert most recently toured in a stage production of Little House on the Prairie. Boxleitner was last seen in December's Tron: Legacy.