Jodi Lyn O'Keefe Jodi Lyn O'Keefe

Prison Break alum Jodi Lyn O'Keefe is set to guest-star on Castle, according to The Hollywood Reporter.

O'Keefe will play Kristina Coterra, a sexy and voluptuous reporter who takes a liking to Castle (Nathan Fillion). Of course, last we saw the novelist, he was finally locking lips with Beckett (Stana Katic). Will Kristina come between them?

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O'Keefe, who most recently recurred on Two and a Half Men, will appear in the second episode of the season, which is titled "Cloudy with a Chance of Murder."

Castle returns for its fourth season on Monday, Sept. 24 at 10/9c on ABC.