Jeff Lewis and Jenni Pulos Jeff Lewis and Jenni Pulos

Not every Interior Therapy couple survived their redesign with Jeff Lewis and his assistant Jenni Pulos.

"We had one particular episode where I knew that this one couple wasn't going to make it," Lewis told "By doing exactly what they wanted [I thought], 'They're going to realize that's not the problem,' and it did. They ended up breaking up."

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In the interview below, Lewis and Pulos talk about their latest Bravo series and how they were able to impact many of their clients' lives. Plus: Which house could Jeff not wait to escape?

Interior Therapy with Jeff Lewis airs Wednesdays at 9/8c on Bravo.