The Melrose Place actress' sister called 911 at approximately 2 p.m., according to the site. The fire department and the Ventura County Sheriff's Department responded to the call and paramedics determined she needed to be hospitalized after an examination.
Locklear, 50, recently broke off her engagement to former Melrose Place co-star Jack Wagner.
In 2008, Locklear's doctor called 911 and claimed she was trying to commit suicide after taking prescription medications, but it later turned out to be a false alarm. She was arrested that same year for a DUI.