Sarah Silverman by Rhet Bear/Comedy Central; Kathy Griffin by Mike Ruiz/Bravo Sarah Silverman by Rhet Bear/Comedy Central; Kathy Griffin by Mike Ruiz/Bravo

A pair of funny ladies stole the show Saturday at the Creative Arts Emmys Saturday night.

Kathy Griffin took home her second Emmy, earning the best reality program trophy for Bravo's My Life on the D-List. According to People, Griffin didn't tell Jesus or anyone else to "suck it" in her acceptance speech (as she infamously did in 2007), but it was still bleepable: "Here we go again, f----rs."

The other bleep-worthy moment of the night was Sarah Silverman's two wins for her viral video smash, "I'm F---ing Matt Damon," a clip that aired on Jimmy Kimmel Live and suggested Silverman was cheating on then-boyfriend Kimmel with the Bourne Identity star. The video took home the award for best original music and lyrics and a picture-editing award.

Though Silverman and Kimmel split after five years together in July, Silverman thanked him in her speech. "Let's be honest, Matt Damon had very little to do with this being popular," she said. "Thanks to the person for whom this whole video was made: Jimmy Kimmel, who broke my heart ohh, who'll always have a place in my heart."

Other winners at the event were Cynthia Nixon for her guest role as a psychopath on Law & Order: Special Victims Unit, Kathryn Joosten for playing Desperate Housewives' Mrs. McCluskey (she also won the award in 2005), Glynn Turman for In Treatment and Tim Conway for his guest work on 30 Rock.

HBO's John Adams claimed the most awards of the night with eight wins, including best costumes for a miniseries, movie or special. Mad Men took home four statues, including best cinematography, and The Simpsons earned its 10th Emmy for best animated half-hour series.

The Creative Arts Emmys will air Saturday, Sept. 20 at 8 pm/ET on E! as the lead-up to the live prime-time gala, which airs the following night on ABC. - Adam Bryant

Use our Online Video Guide to watch clips of Kathy Griffin: My Life on the D-List and Sarah Silverman.

" Kimmel and Silverman Are B****king Up
" Sarah Silverman is "Effing Matt Damon"